Tulathromycin 10-TRV is an antibacterial veterinary product of the macrolide group.
Tulathromycin is a semi-synthetic bacteriostatic antibiotic with a broad spectrum of action against many gram-positive and gram-negative microorganisms, including: Pasteurella multocida, Mannheimia (Pasteurella) haemolytica, Haemophilus somnus, Haemophilus parasuis parasuis, Mycoplasma hyperemia spp., Neisseria spp.
The mechanism of action of tulathromycin is to suppress protein synthesis at the ribosomal level.
The veterinary product is rapidly absorbed from the injection site and reaches its maximum plasma concentration 30 minutes after administration.
Tulathromycin accumulates in neutrophils and alveolar macrophages, as a result of which its increased concentration is reached in the lung tissues.
Tulathromycin is slowly excreted from the body, mainly by the kidneys unchanged. Half-life is about 90 hours.