Salinomycin 12-TRV is an anti-eimeriosis agent of a broad spectrum of action of the ionophore antibiotic group. It has a coccidiostatic effect in the early stages of development of coccidia, reducing the pathological effects of parasites on animals and poultry.
The veterinary product does not cause cross-resistance with monovalent glycoside and bivalent ionophores, reliably protects against the main types of eimeria, and also increases body weight gain and feed digestibility.
Salinomycin sodium is an eimeriostatic of the ionophore group, it is active against most species of eimeria at the stage of sporozoites, trophozoites and schizonts of the first generation. Trichomonas and Cryptosporidia are not sensitive to salinomycin.
The veterinary product damages the transport of sodium and potassium in the oocyst and leads to the death of coccidia at the stage of schizogony.
The mechanism of action of the veterinary product on eimeria is based on the ability of sodium salinomycin to give complex compounds with alkali metal ions. Salinomycin sodium acts as ion carriers and the resulting violation of the intracellular ionic concentration of the parasite leads to its death.
When administered orally, sodium salinomycin is practically not absorbed from the gastrointestinal tract and exerts its effect on the mucous and submucous membranes. It is eliminated mainly unchanged with feces within 3-4 days, in laying birds - with an egg.
Salinomycin 12-TRV, according to the degree of the exposure, belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76).