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Catalog Veterinary products

Ivermectin 1%-TRV

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Ivermectin 1%-TRV

Description:

Ivermectin 1%-TRV is an antiparasitic veterinary product.

Dosage form: solution for injection.

Composition:

1 ml of the veterinary product contains 10 mg of ivermectin, excipients (propylene glycol, benzyl alcohol, 1-methyl 2-pyrrolidone) and water for injection.

Indications for use:

The product is used for therapeutic and prophylactic purposes in cattle and small ruminants with dictyocaulosis, haemonchosis, thelaziosis, strongyloidosis, esophagostomosis, bunostomosis, habertiosis, trichocephalosis, sifunculatosis, hypodermosis, psarcosis, psarcosis. In pigs with ascariasis, esophagostomosis, strongyloidosis, trichocephalosis, metastrongylosis, stefanurosis, hematopinosis and sarcoptic mange.

Method of administration and dosage:

The veterinary product is administered intramuscularly or subcutaneously once.

Cattle

subcutaneously, in the area of the arm at a dose of 1 ml per 50 kg (0.2 mg of active substance per 1 kg) of the animal weight.

Sheep, goats

subcutaneously, in the back third of the neck at a dose of 1 ml per 50 kg (0.2 mg of active substance per 1 kg) of the animal weight.

Pigs

intramuscularly, in the area of the ear base at a dose of 1 ml per 33 kg (0.3 mg of active substance per 1 kg) of the animal weight.

In case of severe damage to animals with sarcoptoidosis, the treatment is carried out twice with an interval of 8-10 days.

Pharmaceutical properties

Ivermectin is a macrocyclic lactone with a broad spectrum of antiparasitic action on the imaginal and larval phases of development of nematodes in the gastrointestinal tract and lungs, as well as ticks, insects and gadfly larvae parasitizing farm animals.

The mechanism of action of the veterinary product on the parasite organism is that ivermectin stimulates the release of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in presynaptic neurons, causing the transmittance of signals from the nerve cell to the muscle tissue cell, it blocks the transmission of nerve impulses, causing the paralysis and death of the parasite.

There is no cross-resistance to other antiparasitic veterinary products (benzimedazole, cholinesterase inhibitors).

The veterinary product is rapidly absorbed from the injection site and penetrates into the organs and tissues of the animal, providing a long-term antiparasitic effect. The therapeutic concentration is maintained for 10-12 days after administration.

Ivermectin is partially metabolized in the liver, excreted from the body mainly with bile and urine, in lactating animals - with milk. Ivermectin is rapidly destroyed in the external environment.

Ivermectin 1%-TRV, according to the degree of exposure, is classified as a low-hazard substance (hazard class 4 according to GOST 12.01.007-76).