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Catalog Veterinary products Antibiotic

Tilmofid-TRV

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Tilmofid-TRV

Description:

Tilmofid-TPV is an antimicrobial veterinary product.

Dosage form: oral powder.

Composition:

1 g contains 200 mg of tilmicosin, excipients (silicon dioxide) and filler (dextrose).

Indications for use:

The drug is used to treat pigs with diseases of the respiratory system, gastrointestinal tract and genitourinary system of bacterial etiology caused by pathogens sensitive to tilmicosin, including: pasteurellosis, staphylococcosis, streptococcosis, mycoplasmosis, swine dysentery.

Method of administration and dosage:

The drug is administered orally for 3-14 days in the following doses

Pigs

individually 0.75-1.0 g per 10 kg of animal body weight once or twice a day;

group method - 1-2 kg of the drug per ton of feed or drinking water.

Pharmaceutical properties

TIlmicosin, which is part of the drug, is a semi-synthetic macrolide antibiotic with a broad spectrum of action.

The drug is active against gram-positive (Staphylococcus spp., Streptococcus spp., Corynebacterium spp.), gram-negative microorganisms (Pasteurella spp., Haemophilus spp., Bordetella bronchiseptica, Ornithobacterium rhinotracheale, Actinobacillus pleuropneumonia, Brachyspira hyodysenteriae, Mannheimia haemolytica), actinomycetes (Actinomyces pyogenes) and mycoplasmas (Mycoplasma spp.).

The mechanism of antimicrobial action consists of blocking protein synthesis in the microbial cell at the ribosome level.

The drug is well absorbed from the gastrointestinal tract when administered orally and penetrates into all organs and tissues of the body, primarily into the tissues of the respiratory system, and accumulates in alveolar macrophages. After 2-3 hours, tilmicosin reaches its maximum level in the blood serum, moderately binds to plasma proteins (less than 30%), therapeutic concentrations are maintained in the body for 24 hours.

Tilmicosin is excreted from the body mainly unchanged, mostly with bile and feces, and partly with urine. In case of liver and kidney dysfunction, the excretion period may increase.