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Catalog Veterinary products Antibiotic

Tiamulin 80-TRV

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Tiamulin 80-TRV

Description:

Tiamulin 80-TPV is an antimicrobial veterinary product.

Dosage form: oral powder.

Composition:

1 gram contains 800 mg of tiamulin hydrogen fumarate and excipients (dextrose, lactose).

Indications for use:

Tiamulin 80-TRV is used as a therapeutic agent in pigs with dysentery, enzootic pneumonia, actinobacillus pleuropneumonia, proliferative enteropathy and intestinal spirochetosis.

Method of administration and dosage:

The veterinary product is administered therapeutically orally individually or in groups.

Pigs

dysentery - 0.125-0.15 kg / ton of feed (5-6 mg of tiamulin per 1 kg of animal weight) for 3-5 days (if necessary, up to 10 days);

respiratory diseases (enzootic pneumonia, pleuropneumonia) - 0.25 kg / ton of feed (10 mg of tiamulin per 1 kg of animal weight) for 10 days

ileitis - 0.125-0.187 kg / ton of feed (5-7.5 mg of tiamulin per 1 kg of animal weight) within 14 days

spirochetosis - 0.125 kg / ton of feed (5 mg of tiamulin per 1 kg of animal weight) for 7-10 days.

Pharmaceutical properties

Tiamulin 80-TRV is an antibacterial veterinary product of the pleuromutilin group.

Tiamulin hydrogen fumarate, which is active substance of the veterinary product, has a broad spectrum of antibacterial action, suppressing protein synthesis of the microbial cell at the ribosomal level, and is highly active against: mycoplasmas, including - Mycoplasma hyopneumoniae, Mycoplasma hyosynoviae, Mycoplasma hyorhinis; brachispir - Brachyspira hyodysenteriae, Brachyspira pilosicoli; gram-positive aerobes, including aerobic cocci - Staphylococcus spp., Streptococcus spp. and anaerobes Clostridium perfringens; gram-negative anaerobes, including Lawsonia intracellularis, Bacteroides spp., Fusobacterium spp. and aerobes Actinobacillus pleuropneumoniae, Pasteurella multocida.

Tiamulin hydrogen fumarate has no effect on Enterobacteriaceae bacteria, including Salmonella spp. and Escherichia coli.

The mechanism of bacteriostatic action of tiamulin hydrogen fumarate is to suppress protein synthesis in a microbial cell at the ribosomal level.

Tiamulin hydrogen fumarate is rapidly absorbed in the gastrointestinal tract and rapidly metabolized in organs and tissues of the body. The maximum concentration is achieved in pigs' organisms - 2 hours after administration of the veterinary product and remains at a therapeutic level for 18-24 hours.

Tiamulin hydrogen fumarate is metabolized in the liver to inactive metabolites and is excreted from the body mainly in feces and, to a lesser extent, in urine.

Tiamulin 80-TRV, according to the degree of the exposure, belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76).