Stovek

Oxytetracycline 200 LA-TRV

Description:

Oxytetracycline 200 LA-TRV is an antibacterial veterinary product.
Dosage form: solution for injection.

Composition:

1 ml of the drug contains 200 mg of oxytetracycline dehydrate, excipients (polyvinylpyrrolidone, 1-methyl-2-pyrrolidone, sodium hydroxymethanesulfinate, magnesium oxide, benzyl alcohol, monoethanolamine, propylparaben) and solvent (water).

Indications for use:

The drug is indicated for cattle, pigs, small ruminants in case of infectious diseases caused by pathogens sensitive to oxytetracycline, including: diseases of the respiratory system, gastrointestinal tract and genitourinary system; pleurisy, pasteurellosis, colibacillosis, salmonellosis, streptococcosis, erysipelas, atrophic rhinitis, enzootic abortion, mastitis, metritis-mastitis-agalactia syndrome, keratoconjunctivitis, footrot, purulent synovitis, umbilical sepsis, abscess, peritonitis, wound and postpartum infections, anaplasmosis, as well as secondary infections in viral diseases.

Method of administration and dosage:

The drug is administered to animals once, deep intramuscularly at a dose of 1 ml of the drug per 10 kg of animal body weight (20 mg of oxytetracycline per 1 kg of animal body weight), if necessary, the drug is repeated after 72 hours (three days).

If the dose of the drug exceeds 20 ml for cattle, 5 ml for small ruminants and pigs, then the drug is administered in several sites.

Pharmaceutical properties

Oxytetracycline, as a part of the drug, has a wide spectrum of antibacterial effect. Effective against most gram-negative (Escherichia coli, Klebsiella spp., Salmonella spp., Proteus spp., Campylobacter spp., Pseudomonas aeruginosa, Bordetella spp., Pasteurella spp., Haemophilus spp., Actinobacillus spp., Brucella spp.) and gram-positive bacteria (Staphylococcus spp., Streptococcus spp., Listeria monocytogenes, Corynebacterium spp., Erysipelothrix rhusiopathiae, Fusobactemm necrophorum, Clostridium spp.), Mycoplasma spp., Chlamydia spp., Rickettsia spp., Borrelia spp.

The drug acts bacteriostatically. Oxytetracycline binds to the 30-S subunit of ribosomes in a bacterial cell. This prevents the inclusion of new amino acids in the peptide chain under construction and leads to the death of microorganisms.

After intramuscular injection, the drug is well absorbed from the injection site and penetrates into most organs and tissues of the body. It reaches the maximum concentration in tissues 30 minutes after administration. The therapeutic level of the antibiotic in the tissues is maintained for 72 hours after a single injection of the drug.

The drug is excreted from the body mainly with urine and bile secretions, in lactating animals - with milk.