Oxytetracycline hydrochloride belongs to the derivatives of tetracycline antibiotics.
Oxytetracycline hydrochloride has a broad spectrum of antimicrobial action, effective against gram-positive microorganisms: Staphylococcus spp., Streptococcus spp., Corynebacterium spp., Clostridium spp., Erysipelothrix rhusiopathiae, Actynomyces spp. and etc.; and gram-negative: Escherichia coli, Pasteurellas pp., Salmonella spp., Brucella spp. and etc.; rickettsia, chlamydia and mycoplasma, protozoa (anaplasma, leptospira, spirochetes).
The veterinary product is especially effective against Escherichia coli and Salmonella spp.
The mechanism of action of oxytetracycline hydrochloride is to inhibit protein synthesis of bacterial cells by blocking the binding of aminoacyl-tRNA to the OS subunit of ribosomes.
Oxytetracycline hydrochloride is well absorbed into the bloodstream from the gastrointestinal tract and is rapidly distributed in the organs and tissues of the body. The maximum concentration in blood plasma is reached within 1-2 hours after administration of the veterinary product and remains at a therapeutic level for 10-12 hours.
Oxytetracycline hydrochloride is practically not metabolized and is excreted from the body mainly with feces, partly with urine.
Oxytetracycline 100-TRV belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76) according to its exposure.