Gentamicin is an antibiotic from the aminoglycoside group. Gentamicin is bactericidal and is active against many strains of Gram-positive and Gram-negative pathogens including species of Escherichia coli, Salmonella spp., Klebsiella spp., Campylobacter spp., Pseudomonas aeruginosa, Proteus spp., Treponema hyodysenteriae, Corynebacterium. Staphylococcus spp. (included strains resistant to penicillin and methicillin). The veterinary medicinal product is less active against streptococci, does not act on anaerobic bacteria, pathogenic fungi and viruses.

Gentamicin, actively penetrating the bacterial cell membrane, binds to the 30S subunit of bacterial ribosomes and inhibits the protein synthesis of the pathogen.

After intramuscular administration, it is rapidly and almost completely absorbed. The maximum concentration in blood plasma occurs after 30-90 minutes and is maintained at a therapeutic level for 6-8 hours. Crosses the placenta. Not metabolized.

Gentamicin is excreted unchanged in microbiologically active form predominantly via the kidneys (70-95%), partly via faecal excretion.