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Catalog Veterinary products Antibiotic

Doxygil 50

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Doxygil 50

Description:

Doxygil 50 is an antimicrobial veterinary product.

Dosage form: oral powder.

Composition:

1 gram contains doxycycline hyclate - 500 mg as active substance, excipients: sodium citrate, citric acid, dextrose.

Indications for use:

Doxygil 50 is used as a therapeutic agent in calves, pigs and poultry for colibacillosis, salmonellosis, pasteurellosis, mycoplasmosis and other infectious diseases of the gastrointestinal tract, respiratory system, genitourinary system caused by microorganisms sensitive to doxycycline.

Method of administration and dosage:

The veterinary medicinal product is administered to animals and poultry individually or in groups in drinking water.

Calves up to 3 months

a single dose - 0.10 gram per 10 kg of animal body weight, twice a day in drinking water for 3-5 days.

Pigs

0.2 gram of the veterinary medicinal product per 10 kg of animal body weight, twice a day in drinking water for 4-6 days.

Poultry

20-40 mg per 1 kg of body weight in drinking water for 3-5 days.

Pharmaceutical properties

Doxycycline is a semisynthetic tetracycline derivative (oxytetracycline derivative). Active against gram-positive and gram-negative microorganisms, incl. Actinobacillus pleuropneumoniae, Clostridium spp., Escherichia coli, Staphylococcus spp., Streptococcus spp., Haemophilus spp., Pasteurella spp., As well as Mycoplasma spp., Rickettsia spp., Chlamydia spp. Proteus, Pseudomonas aeruginosa, pathogenic fungi are not sensitive to the veterinary medicinal product.

The mechanism of the bacteriostatic action of the antibiotic -it exerts its action by inhibiting the protein synthesis by reversible binding to the 30S ribosomal subunit of microorganisms sensitive to the veterinary medicinal product.

Doxycycline is well absorbed into the bloodstream from the gastrointestinal tract and widely distributed in the organisms. The maximum concentration of the antibiotic in the blood serum is reached after 2-4 hours and is maintained at a therapeutic level for at least 18-24 hours after using the veterinary medicinal product.

Doxycycline is excreted primarily in faeces and in urine, in poultry – in eggs.