Doxycycline is a semisynthetic antibiotic of the tetracycline series with a bacteriostatic effect. It is active against gram-positive and gram-negative bacteria (Staphylococcus spp., Streptococcus spp., Listeria monocytogenes, Clostridium spp., Salmonella spp., Enterobacter spp., Moraxella spp., Klebsiella spp., Bordetella coli ), as well as for Rickettsia spp., Treponema spp., Mycoplasma spp. and Chlamydia spp. Proteus, Pseudomonas aeruginosa, pathogenic fungi are not sensitive to the veterinary product.
The mechanism of action of the antibiotic -it exerts its action by inhibiting the protein synthesis of the microbial cell at the ribosome level.
Doxycycline is well absorbed from the gastrointestinal tract and is rapidly distributed in organs and tissues of the body. The maximum concentration in the blood serum is reached after 2-4 hours and is maintained at a therapeutic level for at least 18-24 hours after using the veterinary product.
Doscycline is excreted from the body primarily in urine and faeces.