Ciprofloxacin aqua belongs to the antibacterial veterinary products of the fluoroquinolone group and has a wide spectrum of antimicrobial and anti-mycoplasma action and acts both on proliferating microorganisms and vegetative bacteria. Active against gram-positive and gram-negative bacteria, including:
Staphylococcus spp., Streptococcus spp., Clostridium spp., Actinobacillus spp., Escherichia coli, Salmonella spp., Enterobacter spp., Haemophilus spp., Klebsiella spp., Pasteurella spp., Bordetella spp., Proteus mirabilus, Proteus vulgaris, Pseudomonas aeruginosa, Campylobacter spp., Erysipelothrix rhusiopathiae, Bacteroides, Fusobacterium necrophorum, Mycoplasma spp. and other.
The mechanism of the bactericidal action of ciprofloxacin is in blocking bacterial DNA gyrase, which leads to disruption of bacterial division due to inhibition of DNA synthesis, as well as in the development of morphological changes in the cell wall and membranes of the microbial cell.
Acts on gram-negative microorganisms in rest and division phases, has an effect on gram-positive microorganisms only in division phase.
Does not have embryotoxic, teratogenic and hepatotoxic effects.
When the veterinary product is administered orally, ciprofloxacin is well and rapidly absorbed in the gastrointestinal tract and penetrates into all organs and tissues, reaching the maximum concentration in the blood, depending on the type of animal, after 0.5- 2.5 hours (bioavailability over 70%). The therapeutic concentration of ciprofloxacin in the blood of animals is maintained for 7-10 hours. It is excreted from the body of animals mainly in urine unchanged, as well as in the form of metabolites, the rest is excreted by the gastrointestinal tract (with faeces and bile).
Ciprofloxacinum aqua, according to the degree of exposure to the body, refers to low-hazard substances (hazard class 4 according to GOST 12.1.007-76).
