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Catalog Veterinary products Antibiotic

Amoxicillin 80-TRV

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Amoxicillin 80-TRV

Description:

Amoxicillin 80-TRV is an antimicrobial veterinary product.

Dosage form: oral powder.

Composition:

1 gram contains 800 mg of amoxicillin trihydrate as an active ingredient and excipients: sodium anhydrous carbonate, sodium hydroxide, dextrose.

Indications for use:

Amoxicillin is ansemisynthetic penicillin group antibiotic, which has a wide spectrum of antibacterial action. It is active against many microorganisms, including: gram-positive: aerobic cocci - Staphylococcus spp., Streptococcus spp., aerobic non-spore-forming bacteria - Listeria monocytogenes, anaerobic spore-forming bacteria - Clostridium spp, Actynomyces spp., anaerobic non-spore-forming - Erysipelothrix rhusiopathiae, Corynebacterium spp.; gram-negative: aerobic cocci - Actinobacillus spp., aerobic spirochetes - Leptospira spp .; aerobic bacteria - Escherichia coli, Salmonella spp., Klebsiella spp., Haemophilus spp., Pasteurella spp., Bordetella bronchiseptica, Moraxella spp., Proteus mirabilis, anaerobic non-spore-forming - Fusobacterium necrophorum

Method of administration and dosage:

The veterinary product is administered orally with water or food, individually or in groups, for 3-5 days.

Pigs up to 6 months of age

with water in groups - 100 gram of the veterinary product (80 g of active substance) per 1000 liters of water;

with feed in groups - 100 gram of the veterinary product (80 g of active substance) per 1 metric ton of the feed.

Pigs over 6 months of age

with water in groups - 200 gram of the veterinary product (160 g of active substance) per 1000 liters of water;

with feed in groups - 200 gram of the veterinary product (160 g of active substance) per1 metric ton of the feed.

Poultry

with water in groups - 100-250 gram of the veterinary product (80 g-200 g of active substance) per 1000 l of drinking water;

with feed in groups - 10-20 mg of the veterinary product (8 mg-16 mg of active substance) per 1 kg of body weight.

Calves, piglets

individually - 15-30 mg of the veterinary product (12-24 mg of active substance) per 1 kg of body weight once a day.

Poultry (broiler chickens, turkeys)

individually - 10-20 mg of the veterinary product (8 mg-16 mg of active substance) per 1 kg of body weight.

Pharmaceutical properties

Amoxicillin is ansemisynthetic penicillin group antibiotic, which has a wide spectrum of antibacterial action. It is active against many microorganisms, including: gram-positive: aerobic cocci - Staphylococcus spp., Streptococcus spp., aerobic non-spore-forming bacteria - Listeria monocytogenes, anaerobic spore-forming bacteria - Clostridium spp, Actynomyces spp., anaerobic non-spore-forming - Erysipelothrix rhusiopathiae, Corynebacterium spp. gram-negative: aerobic cocci - Actinobacillus spp., aerobic spirochetes - Leptospira spp .; aerobic bacteria - Escherichia coli, Salmonella spp., Klebsiella spp., Haemophilus spp., Pasteurella spp., Bordetella bronchiseptica, Moraxella spp., Proteus mirabilis, anaerobic non-spore-forming - Fusobacterium necrophorum

Amoxicillin is not active against microorganisms that produce β-lactamase and does not act on penicillin-resistant strains of microorganisms.

The mechanism of the bactericidal action of the antibiotic is to interfere with the synthesis of the cell wall by inhibiting the enzymes transpeptidase and carboxypeptidase, causing a damage of the osmotic pressure in the bacterial cell, which leads to the death of bacteria at the stage of their growth.

Amoxicillin is well absorbed into the bloodstream from the gastrointestinal tract and is rapidly distributed in the organs and tissues. The maximum concentration in blood plasma is reached within 1-2 hours after administration of the veterinary product.

With a constant intake of an antibiotic with water or food, therapeutic concentrations are maintained in the body throughout the entire course of treatment.

Amoxicillin is practically not metabolized and is excreted mainly unchanged with urine and, to a lesser extent, with bile.

Amoxicillin 80-TRV, according to the degree of the exposure, belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76).