Stovek

Amocol 50

Description:

Amocol 50 is a combined antimicrobial veterinary product, oral powder

Composition:

1 gram contains 500 mg of amoxicillin trihydrate and 4 million IU of colistin sulfate as active ingredients and excipients - sodium citrate, citric acid, sodium carbonate anhydrous, dextrose.

Indications for use:

Amocol 50 is used as a therapeutic agent for piglets, calves and poultry with colibacillosis, salmonellosis, pasteurellosis, hemophilia, necrobacteriosis, swine erysipelas and other diseases, the causative agents of which are sensitive to the components of the veterinary product .

Method of administration and dosage:

The veterinary product is used for piglets, calves and poultry in group or individual ways with water or milk for drinking for 3-5 days.

Calves, piglets

3 gram of the veterinary product per 100 kg of body weight, bid.

Poultry

300 gram of the veterinary product per 1000 liters of drinking water. For a poultry, a solution of the veterinary product is prepared based on the need for water for one day.

Pharmaceutical properties

Amoxicillin is a penicillin group semi-synthetic antibiotic. It has a wide spectrum of antimicrobial action. Erysipelothrix rhusiopathiae, Staphylococcus spp., Corynebacterium spp., Clostridium spp., Salmonella spp., Fusobacterium necrophorum, Haemophilus spp., Pasteurella spp., Proteus spp., Escherichia coli and other microorganisms are sensitive to Amoxicillin.

Amoxicillin inhibits the synthesis of the bacterial cell wall by inhibiting the enzymes transpeptidase and carboxypeptidase, which leads to disruption of the osmotic balance and death of bacteria.

Amoxicillin is well absorbed into the bloodstream from the gastrointestinal tract and is rapidly distributed in the organs and tissues. The maximum concentration in blood plasma is reached within 1-2 hours after administration. It is excreted with urine and bile.

Colistin sulfate is a mixture of polypeptides produced by several strains of Bacillus polymyxia. It has a bactericidal effect against some aerobic gram-negative microorganisms.

The mechanism of action of colistin sulfate is associated with a damage of the permeability of the cytoplasmic membrane of bacteria sensitive to it.

The colistin sulfate is not destroyed and is practically not absorbed into the blood in the gastrointestinal tract of animals. It does not accumulate in organs and tissues; it is excreted with feces.

The product belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76) according to its exposure.

Amocol 50

Amocol 50

Calves, piglets

Poultry