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Catalog Veterinary products

Amprolium 100-TRV

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Amprolium 100-TRV

Description:

Amprolium 100-TPV is an anticoccidial product.

Dosage form: oral powder.

Composition:

1 gram contains 900 mg of amprolium hydrochloride as an active ingredient and excipients (dextrose).

Indications for use:

Amprolium 100-TRV is used as a therapeutic and prophylactic agent for eimeriosis in broiler chickens, replacement poultry, breeding poultry, as well as cattle and small cattle.

Method of administration and dosage:

The veterinary product is administered orally to poultry, large and small cattle in groups with feed or water:

for prophylactic purposes 130-150 gram per ton of drinking water or feed (120 mg of active substance per 1 liter of water or 1 kg of feed);

for therapeutic purposes, 250-300 gram per ton of drinking water or feed (240 mg of active substance per 1 liter of water or 1 kg of feed) for 5-10 days in a row, followed by a transition to a prophylactic dose

For broilers, for prophylactic purposes, the veterinary product is used from 3-5 days of age.

Replacement youngsters are prescribed from 1 day of life and canceled 3 weeks after transfer for keeping in a cage.

Layers with floor maintenance - are prescribed from 1 day of life to 5 weeks of age in a prophylactic dose.

Turkeys - from 1 day of age to 10 weeks of age.

For prophylactic purposes, the veterinary product is administered to calves within 21 days, to sheep - within 5 days.

Pharmaceutical properties

Amprolium 100-TRV is a broad spectrum anti-eimeriosis veterinary product. Amprolium hydrochloride is a pyrimidine derivative, is active against the Eimerian genus of other Eimeria species parasitizing in poultry, and is compatible with vitamins and feed additives used in poultry farming.

Amprolium hydrochloride inhibits the development of eimeria at the stage of merogony of the first and second generation, the mechanism of action of which is due to the proximity of its chemical structure to thiamine (Vitamin B1), which is necessary for the vital activity of coccidia. Due to active transport, amprolium penetrates the parasite cell better than thiamine and occupies the active binding sites of the vitamin, which leads to disruption of carbohydrate metabolism and the death of the parasite.

Amprolium hydrochloride does not penetrate the cell membranes of the intestinal mucosa of poultry and mammals, and has low toxicity for warm-blooded animals.

Amprolium is practically not absorbed in the gastrointestinal tract, exhibiting anti-eimeriosis effect on mucous and submucous membranes. It is excreted mainly unchanged: with feces within 3-4 days and does not interfere with the formation of immunity to eimeriosis.

Amprolium 100-TRV, according to the degree of exposure, is classified as a low-hazard substance (hazard class 4 according to GOST 12.01.007).